Adequan i.m. – Advanced Joint Therapy for Horses

What Is Adequan i.m?

Adequan i.m.  is a prescription veterinary medication manufactured by American Regent Animal Health and is also know as(polysulfated glycosaminoglycan, PSGAG). It is the first and only FDA‑approved PSGAG injection for horses, designed to treat non‑infectious degenerative and/or traumatic joint dysfunction. Adequan is widely trusted by veterinarians and horse owners to manage lameness, stiffness, and osteoarthritis in equine athletes.

How Adequan Works

Adequan targets the underlying causes of joint degeneration:

• Inhibits proteolytic enzymes that degrade cartilage.
• Stimulates cartilage repair by increasing proteoglycan synthesis.
• Improves synovial fluid quality by reducing protein levels and increasing hyaluronic acid.
• Restores joint function and reduces inflammation, improving mobility and performance.

Composition

Each 5 mL dose contains:

• Polysulfated glycosaminoglycan (PSGAG): 500 mg
• Water for injection
• Sodium chloride (to adjust tonicity)
• Sodium hydroxide/hydrochloric acid (to adjust pH)

Recommended Administration

• Route: Intramuscular injection only (not intra‑articular).
• Dosage: 500 mg (5 mL) every 4 days for 28 days (7 injections total).
• Packaging: Single‑dose 5 mL vials or preserved multi‑dose 50 mL vials (100 mg/mL).
• Onset: Clinical improvement often observed within 2–4 weeks.

Indications

Adequan i.m. is indicated for:

• Degenerative joint disease (DJD) in horses.
• Traumatic joint dysfunction causing lameness.
• Performance horses requiring enhanced mobility and recovery.
• Long‑term management of osteoarthritis.

Benefits of Adequan i.m.

• FDA‑approved for equine use.
• Disease‑modifying action: Not just symptom relief, but cartilage protection.
• Improves mobility: Horses regain flexibility and comfort.
• Enhances performance: Better stamina and reduced downtime.
• Safe alternative to chronic NSAID use.

Safety & Precautions

• Side effects: Rare but may include mild injection site reactions.
• Contraindications: Not for use in horses intended for human consumption.
• Veterinary supervision required: Federal law restricts Adequan to licensed veterinarians.
• Competition guidelines: Trainers should confirm local racing regulations before use.

Global Availability

Prime Vet Meds ensures secure and reliable access to Adequan i.m. across multiple regions:

• UK & Ireland – Veterinary‑approved sourcing with fast delivery.
• Canada & USA – Licensed distribution with compliance to local regulations.
• Australia & New Zealand – Safe import channels for equine use.
• Europe (Germany, France, Spain, Portugal, Switzerland, etc.) – Multilingual support and EU‑compliant supply chain.

Why Choose Prime Vet Meds?

• Authenticity Guaranteed: Genuine Adequan i.m. injections.
• Worldwide Shipping: Covering major European countries, UK, Canada, and Australia.
• Expert Support: Guidance on safe handling, dosage, and administration.
• Customer Confidence: Transparent policies, secure checkout, and responsive service.

How adequan i.m Works

Adequan i.m Canine polysulfated glycosaminoglycan is administered two times a week for four weeks. The drug is injected intramuscularly to ensure it reaches the critical parts of the joint. It goes to work in the joint in about two hours and stays in the joint for about three days.With Adequan Canine you should see signs of improvement within four weeks. Your dog may begin to act like the playful, active dog you remember.Adequan i.m

Cautions:

Adequan i.m Canine polysulfated glycosaminoglycan or PSGAG should not be used in dogs who are hypersensitive to PSGAG or who have a known or suspected bleeding disorder. It should be used with caution in dogs with renal or hepatic impairment. Possible side effects pain at injection site, diarrhea and abnormal bleeding were mild, transient and self-limiting. Safety studies of PSGAG in breeding, pregnant or lactating dogs have not been conducted.

 Storage Conditions:

Store at controlled room temperature up to 25°C (77°F) (See USP).

Frequently Asked Questions:

Q: What are the signs of canine arthritis?
It is important to note that arthritis occurs before clinical signs are shown. The beginning stages of this disease are not easily recognized. If your dog is suffering from arthritis, you will most likely see one or more of the following signs: lagging behind on walks, reluctance to walking, running, climbing stairs, jumping or playing. Additional signs may include: sluggishness, tiredness, low activity, reluctance to extend rear legs, aggressive or withdrawn behavior or other personality/behavioral changes.

Q: How do I know if my dog is at risk for this disease?
Canine arthritis does not discriminate. This disease can affect all breeds of dogs, but there are certain risk factors that you should be aware of, including: overweight, high activity levels for long periods of time, breed inherited traits, such as hip dysplasia, joint trauma, large breed and over the age of five.

Adequan i.m. is a trusted veterinary solution for equine joint dysfunction, offering cartilage protection, improved synovial fluid quality, and enhanced mobility. With FDA approval and proven clinical efficacy, it remains a cornerstone of equine osteoarthritis management. Prime Vet Meds is committed to providing safe, authentic, and accessible Adequan worldwide, ensuring your horses perform at their best.