Acepromazine – Trusted Veterinary Sedative & Tranquilizer for Dogs, Cats & Horses

What Is Acepromazine?

Acepromazine maleate is a widely used veterinary tranquilizer and sedative. It belongs to the phenothiazine class of neuroleptic agents and is trusted by veterinarians worldwide for its ability to calm animals, reduce anxiety, and provide chemical restraint. Available in both injectable solution (10 mg/mL) and oral tablet formulations, Acepromazine is a cornerstone of veterinary medicine for dogs, cats, and horses.

How Acepromazine Works

• Central nervous system action: Acepromazine depresses dopamine receptors in the brain, producing sedation and tranquilization.
• No analgesia: It calms animals but does not relieve pain, so it is often combined with analgesics for surgical procedures.
• Pre‑anesthetic use: Reduces anxiety and stress before anesthesia, making induction smoother.
• Chemical restraint: Provides safe sedation for handling, grooming, or minor veterinary procedures.

Indications

Acepromazine is indicated for:

• Dogs & Cats:
  • Calming anxious pets during travel, grooming, or veterinary visits.
  • Pre‑anesthetic medication to reduce stress before surgery.
  • Chemical restraint for minor procedures.
• Horses:
  • Sedation during transport, dental work, or minor surgical interventions.
  • Used to calm fractious horses for safe handling.

Benefits

• Reliable sedation: Provides predictable calming effects across species.
• Versatile use: Suitable for dogs, cats, and horses.
• Pre‑anesthetic support: Reduces stress and improves anesthesia safety.
• Long duration: Sedation typically lasts 6–8 hours.
• Trusted worldwide: Acepromazine is one of the most widely used veterinary tranquilizers.

Administration & Dosage

• Formulations: Injectable solution (10 mg/mL) and oral tablets.
• Route: Intravenous (IV), intramuscular (IM), subcutaneous (SC), or oral.
• Dosage:
  • Dogs: 0.02–0.05 mg/kg.
  • Cats: 0.02–0.05 mg/kg.
  • Horses: 0.02–0.04 mg/kg.
• Onset: 15–60 minutes depending on route.
• Duration: 6–8 hours of sedation.

Safety & Precautions

• Side effects: Hypotension, lowered body temperature, prolonged sedation.
• Contraindications: Avoid in animals with cardiovascular disease, shock, or seizure disorders.
• Not for pain relief: Must be combined with analgesics for painful procedures.
• Veterinary supervision required: Federal law restricts use to licensed veterinarians.

Global Availability

Prime Vet Meds ensures secure and reliable access to Acepromazine across multiple regions:

• UK & Ireland – Licensed for dogs, cats, and horses.
• Canada & USA – FDA‑approved injectable and oral formulations.
• Australia & New Zealand – Available through veterinary prescription.
• Europe (Germany, France, Spain, Portugal, Switzerland, etc.) – EU‑compliant supply chain ensures safe distribution.

Why Choose Prime Vet Meds?

• Authenticity Guaranteed: Genuine Acepromazine injections and tablets sourced from trusted suppliers.
• Worldwide Shipping: Covering major European countries, UK, Canada, and Australia.
• Expert Support: Guidance on safe handling, dosage, and administration.
• Customer Confidence: Transparent policies, secure checkout, and responsive service.

Acepromazine Maleate Injection is used for sedation, tranquilization and as a pre-anesthetic agent in horses, dogs and cats. Each ml contains 10 mg Acepromazine Maleate. Can be used as an aid in controlling animals during examination, treatment and minor surgical procedures. Maleate has a depressant effect on the central nervous system and therefore causes sedation, muscular relaxation and a reduction in spontaneous activity. It acts rapidly, exerting a prompt and pronounced calming effect. It is an effective pre-anesthetic agent and lowers the dosage requirement of general anesthetics.

Acepromazine Maleate Injection may be given intravenously, intramuscularly or subcutaneously. The general dosage of Maleate Injection for horses is 2-4 mg per 100 lbs body weight; dogs 0.25-0.5 mg per lb body weight; for cats 0.5-1.0 mg per lb body weight.

Not for use in animals hypersensitive (allergic) to it or other phenothiazines. Use with caution in debilitated or geriatric animals and those with liver or heart disease. Do not use in pregnant or lactating animals (female animals nursing their young) unless benefits outweigh the risks. Do not use in animals with hypovolemia (low blood volume), anemia, or shock. Do not use in animals with tetanus or strychnine toxicity. May cause seizures. Do not use with animals known to have seizures or are having medical procedures known to cause seizures (e.g., myelograms). When used to aid in restraint, the sedative effect can be overridden and the animal may bite or jump unexpectedly. Promace is an inappropriate medication for the treatment of aggression since it can make aggressive animals less predictable, and can interfere with training. Causes low blood pressure and inability to maintain proper body temperature.  ACEPROMAZINE ACEPROMAZINE ACEPROMAZINE ACEPROMAZINE

Does not provide any pain relief. Giant breeds, greyhounds, and boxers may be more sensitive to its effects; terriers may be less sensitive. Effects may last 6-8 hours, and results may not be consistent when given orally. Consult with your veterinarian regarding the physical examinations and laboratory testing necessary prior to and during treatment with promace.

Drug, Food, and Test Interactions:
Consult your veterinarian before using promace with vitamins, supplements, atropine, central nervous system (CNS) depressant drugs (such as barbiturates, narcotics, and antidepressants), organophosphate dewormer or insecticide, kaopectate, Pepto-Bismal, other antidiarrheal mixures, antacids, propranolol, and epinephrine. May have an adverse heart reaction if used with quinidine. Phenytoin levels and procaine activity may be increased if used with promace.

Acepromazine is a trusted veterinary tranquilizer used for sedation and pre‑anesthetic purposes in dogs, cats, and horses. With its long duration, predictable effects, and versatile applications, it remains a cornerstone of veterinary medicine worldwide. Prime Vet Meds is committed to providing safe, authentic, and accessible Acepromazine, ensuring veterinarians and animal owners have reliable solutions for animal care.